Bioreagents & Antibiotics
High quality bioreagents backed up by Certificate of
Analysis for everyday life science laboratory research use.
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Acrylamide:Bis 40% Solution, 29:1
p/n and sizes: R7732-291, 1L & bulk
p/n and sizes: R7732-371, 1L &
Preblended stock solution of
acrylamide and Bis for safe and convenient use. Eliminates hands on need to weight toxic
acrylamide. Convenient for electrophoresis applications. For research
p/n and sizes: R1397-1g, R1397-5g, &
Polyene antifungal antibiotic from
Streptomyces. Affinity for sterols, primarily ergosterols, of fungal cell membranes. It is used in cell
culture applications to study the formation of ion-permeable channels in fungal cell membranes. Interferes
with fungal membrane permeability by forming channels in the membranes and causing small molecules to leak
out. Active against yeasts also.For research
Molecular Weight : 924.08
Molecular Formula :
CAS : 1397-89-3
Storage : 4°C Protect from light & moisture
Solubility : Soluble in DMSO. Slightly soluble in water
p/n and sizes:
R6952-50g, R6952-100g, &
A β-lactam antibiotic with an amino group side chain attached to
the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan
cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane.
Bactericidal only to growing Escherichia coli Resistance mediated by β-lactamase at cleavage of β-lactam ring
of ampicillin. For
Molecular Weight: 371.39
Molecular Formula: C16H18N3NaO4S
Solubility: Soluble in water (50mg/ml)
p/n and sizes:
R6571-5g, R6571-50g, & bulk
Aminoglycoside antibiotic with bactericidal activity against most Gram-negative
bacteria. Apramycin is used to study protein synthesis translocation-step inhibition in bacteria and prokaryotes.
Harmful by inhalation, in contact with skin and if swallowed.
Solubility: Soluble in water
BES (N,N-Bis(hydroxyethyl)-2aminoethanesulfonic acid)
p/n and sizes:
Highly efficient transformation of mammalian cells with a BES-buffered salt solution (50 mM BES, pH
6.95(transformation crucial factor); 280 mM NaCl; 1.5 mM Na2HPO4). For research
Molecular Weight: 213.25
Molecular Formula: C6H15NO5S
Solubility: Soluble in water
Bicine (N, N-Bis(2-Hydroxyethyl)Glycine)
p/n and sizes:
Generally used for protein purification and other life science applications ranges from
enzyme reaction buffers to electrophoresis buffers.
Molecular Formula: C6H13NO4
p/n and sizes:
R6976-250g, R6976-500g &
Biological buffer for protein and nucleic acid system also as substitute for
cacodylic acid buffer systems. For research use.
Molecular Weight: 209.24
Molecular Formula: C8H19NO5
p/n and sizes:
For use in molecular biology buffer, most commonly TBE buffer, with a pH
Molecular Formula: H3BO3
CAPS (3-(Cyclohexylamino)-1-propanesulfonic acid,
p/n and sizes: R1135-250g,
R1135-500g, & bulk
Alkaline buffer (pH 10-11, concentration 10-50mM, pH adjustment by NaOH)
for protein transfer after SDS polyacrylamide gel electrophoresis on nitrocellulose filters. Also
commonly used to investigate metal-dependent enzymes. For research use.
Physical Appearance: White powder
Molecular Weight: 221.31
Molecular Formula: C6H11NH(CH2)3SO3H
Solubility:Soluble in water
p/n and sizes:
R4800-25g, R1135-100g, & bulk
Carboxypenicillin antibiotic that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by
inactivating transpeptidases on the inner surface of the bacterial cell membrane. Analog to
ampicillin.Antimicrobial spectrum: Gram-positive and Gram-negative bacteria,
Pseudomonas. For research use.
Molecular Weight: 422.36
Molecular Formula: C17H16N2Na2O6S
Soluble in water.
p/n and sizes: R7562-10g,
R7562-50g, & Bulk
Non-denaturing Zwitterionic detergent suitable for use as a solubilizing agent for membrane
proteins due to the disruption of non-specific protein interactions. Ref: Hjelmeland, L.H., Proc. Nat. Acad.
Sci. USA, 77, 6368 (1980) For research use.
Molecular Weight: 614.88
Molecular Formula: C32H58N2O7S
CHES (2-(Cyclohexylamino) ethanesulfonic acid)
sizes: R1034-250g, R1034-500g, &
A common biological buffer. For research use.
Molecular Weight: 207.29
Molecular Formula: C8H17NO3S
sizes: R5675-250g, R5675-1kg, &
Bacteriostatic against gram-negative and gram-positive bacteria. Inhibits protein synthesis by
preventing peptide bond formation by peptidyl transferase. Used in large scale plasmid preparation of low to
moderate copy number plasmids as well as in CAT assays. For research use.
Potency: >900 μg/mg
Molecular Weight: 323.13
Molecular Formula: Cl2CHCONHCH(CH2OH)CH(OH)C6H4NO2
Solubility: Soluble in alcohol
and sizes: R5986-100mg, R5986-1g &
A fungal metabolite possessing potent immunosuppressive properties, inhibits the T-cell receptor
signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin.
Also, Inhibits nitric oxide synthesis induced by interleukin 1α, lipopolysaccharides and TNFα, and blocks
cytochrome c release from mitochondria. For research use.
Molecular Formula: C62H111N11O12
Molecular Weight 1202.61
sizes: R2531-10mg, R2531-100mg &
Antineoplastic antibiotic interferes with nucleic acid synthesis. Also acts on cell
membranes. Inhibitor of reverse transcriptase and RNA polymerase; immunosuppressive agent; intercalates
in DNA. Naturally fluorescent anthracycline antibiotic, anticancer drug. For research
Molecular Weight: 579.98
Molecular Formula: C27H29NO11 ·
Soluble in water. Light/moisture sensitive
sizes: R1059-25g &
Active against Gram-positive and Gram-negative bacteria. Interferes with bacterial cell wall
Semi-synthetic tetracycline. For research use.
Molecular Weight: 480.9
Molecular Formula: C22H24N2O8 . HCl
DTT (DL-Dithiothreitol), Ultra Pure
and sizes: R7634-50g, R7634-500g &
Reducing reagent for proteins and protects the
cysteine residues against oxidation. For research use.
A280 (0.02M, water): <0.05
S-S content: <0.5%
Melting range: 39-43°C
EDTA, Disodium Salt, Ultra Pure
sizes: R9410-1kg & Bulk
A metal chelating agent commonly used in tissue culture media and biological buffers. Ideal for
electrophoresis and molecular biology use. For research use.
Heavy metals (as Pb): ≤0.001%
Molecular Weight: 404.45
Molecular Formula: (HO2CCH2)2NCH2CH2N(CH2CO2H)
5-FOA ((5-Fluoroorotic acid), Monohydrate)
sizes: R7039-5g, R7039-25g, &
Used as a research tool in molecular genetics. Yeast
Selection Reagent. Employed in the selection of resistant strains of Saccharomyces
cerevisiae that possess a mutant URA3 gene which renders them orotidine-5-phosphate decarboxylase deficient.
5-FOA is converted 5-fluorouridine monophosphate (5-FUMP) in yeast cells, which can become incorporated into
RNA or metabolized to the highly toxic 5-fluoro-2-deoxyuridine monophosphate (5-FdUMP). 5-FdUMP is a
potential inhibitor of thyidylate Sythase (TS), causing a cessation in DNA synthesis.
Solubility: 50mg in 1ml (1:1) ammonium hydroxide-water with gentle heating.
Molecular Weight: 174.09
Molecular Formula: C5H3FN2O4
p/n and sizes: R1083-5g, R1083-50g, & Bulk
G418 Sulfate, an aminoglycoside
antibiotic, is related to gentamicin. G418 is toxic to both prokaryotic and eukaryotic cells. It is used primarily
for the selection of eukaryotic expression vectors bearing the related resistance genes. Recommended concentration
varies by cell type; in mammalian cells, 400 mg/L is recommended for initial selection, and then reduced to 200
mg/L for culture maintenance. For research use.
White to off white powder
Molecular Weight: 692.71
Molecular Formula: C20H40N4O10 ·
p/n and sizes: R5640-Bulk
Glycine is a component of Tris-glycine and Tris-glycine-SDS running
buffers for polyacrylamide gel electrophoresis. Glycine is also a component of transfer buffer for Western
blots. For research use.
Molecular Formula: NH2CH2COOH
sizes: R1405-25g, R1405-100g, &
Gentamycin sulfateis a broad spectrum antibiotic that inhibits the growth of a wide variety of Gram-positive and
Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and
colistin; particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. It inhibits bacterial
protein biosynthesis by binding to the 30S subunit of the ribosome. For research use.
Solubility (H2O): 50 mg/ml
Molecular Weight: 575.67
Molecular Formula: C21H43N5O7.H2SO4
p/n and sizes: R5001-500g, R5001-2kg, & Bulk
A strong chaotropic agent used at high concentrations for denaturing native proteins and inactivating RNAses.
For research use.
RNase/DNase Activity: None detected
Molecular Weight: 95.53
Molecular Formula: NH2C(=NH)NH2 · HCl
p/n and sizes:
R5938-500g & Bulk
Chaotropic agent and strong denaturant; solubilizes cells.
For research use.
Molecular Weight: 118.16
Formula: NH2C(=NH)NH2 · HSCN
acid]), Sodium Salt
sizes: R7365-500g, R7365-2kg, &
HEPES is a widely used buffer in biological studies. In cell culture media, it is employed as a substitute for the
bicarbonate buffer at a concentration of 25 mM or as a supplement to the bicarbonate buffer (concentration
10-15mM). The addition of 20mM HEPES to TBE buffer improves the migration behavior of certain samples in the
SSCP analysis (single-strand conformation polymorphism), with a higher resolution especially if small differences
in the sequences between certain bands are wanted. For research use.
Molecular Formula: C8H17N2NaO4S
(N-[2-Hydroxyethyl]piperazine-N'-[3-propanesulfonic acid]) Ultra Pure
sizes: R1605-100g, R1605-500g, &
HEPPS has many properties similar to HEPES. Because of its high
buffer range, it is suited for studies on phosphorylation reactions, especially if tricine (binds metal ions)
cannot be applied. Like HEPES, HEPPS interferes with the Folin protein assay, but not with the Biuret assay. For
Molecular Weight: 252.33
Molecular Formula: C9H20N2O4S
Melting Point: 240-244°C
p/n and sizes: R3128-1g, R3128-25g, & Bulk
Aminoglycoside antibiotic, acts against bacteria, fungi and higher eukaryotes by inhibiting protein synthesis.
Originally developed as an antihelminthic, hygromycin B is used in the research laboratory primarily for the
selection and maintenance of cells that carry the hygromycin resistance gene. For research use.
Solubility: Mammalian cells: 50-1000ug/mL; Plant cells: 20-200ug/mL; Bacteria: 20-200ug/mL; Fungi:
Purity (HPLC) : ≥92%
Potency 1118 µg/mg
Molecular Weight: 527.52
p/n and sizes: R3679-10g, R3679-50g,
An inducer of β-galactosidase used to promote the expression of proteins in cells controlled by the lac operator
system. For blue/white screening, 0.1 mM final IPTG concentration in LB (Luria Broth) media is
recommended. For research use.
Dioxane (GLC): <1ppm
Purity (HPLC): 99.9%
Molecular Weight: 238.31
p/n and sizes: R2538-25g, R2538-100g, &
Aminoglycoside with activity against many Gram-negative bacteria. Binds to ribosomal subunit and inhibits protein
synthesis. Used as a selective agent for the incorporation of NPT II (Neomycin phosphotransferase) (APH3') gene in
plant and animal cells. For research use.
Potency (Dried Substance): ≥670 IU/mg
Soluble in water.
Molecular Weight: 582.58
Molecular Formula: C18H36N4O11 ·
p/n and sizes: R4432-250g, R4432-1kg, & Bulk
A biological buffer mailnly used in plant cell culture. A \"Good Buffer\" because it has a pKa value near
physiological pH, it is not absorbed through cell membranes, and it is essentially transparent to UV light. Used
for culture media. For research
Solubility: soluble in
Molecular Weight: 217.2
Molecular Formula: C6H13NO4S
p/n and sizes: R5007-5mg, R5007-50mg, & Bulk
Acts as an alkylating agent after activation and also supresses the synthesis of nucleic acids. Cell-cycle
non-specific agent, but is most active in the late G1 and early S phases. Activity against Gram positive
bacteria, Gram negative bacteria and Acid fact bacilli. For reserach use.
Source: Streptomyces sp
Solubility: Soluble in ethanol; Slightly soluble in
Molecular Weight: 334.33
Molecular Formula: C15H18N4O5
MOPS (3-(N-Morpholino)PropaneSulfonic acid), Ultra
p/n and sizes: R1132-500g &
Molecular Biology Buffer, component of running buffer, RNA Eletrophoresis. For research use.
Solubility (0.1M, Water)(P/F):
Molecular Formula: C7H15NO4S
p/n and sizes: R3690-10g, R3690-50g, &
Colorimetric and spectrophotometric substrate for detection of
ß-D-Glacotosidase. The cleavage of ONPG releases the yellow dye 4-nitrophenyl and absorption
is measured at 405 - 420 nm by spectrophotometry. For research use.
Molecular Weight: 301.25
Molecular Formula: C12H15NO8
Penicillin G Potassium Salt
p/n and sizes: R1139-250MU, R1139-1000MU, &
Penicillin G was isolated from Penicillium notatum. The
bactericidal effect of this β-lactam antibiotic is based on the irreversible inhibition of transpeptidase,
interfering with the biosynthesis of the cell wall in bacteria. Lactamase sensitive. For research use.
Molecular Formula: C16H17KN2O4S
PIPES (Piperazine-1, 4-bisethanesulfonic
p/n and sizes: R5625-250g, R5625-1kg, &
Molecular Biology Buffer, used for culturing cells in
vitro and other biological applications. For research
Molecular Weight: 302.37
Molecular Formula: C8H18N2O6S2
p/n and sizes: R5312-10mg, R5312-100mg, &
Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and
immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as,
the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins. Rapamycin also inhibits the
activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote
tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and
prevents interaction of mTOR with target proteins in this signaling pathway. For research use.
Purity: ≥ 98%
Solubility: Soluble in DMSO and Methanol
Molecular Formula: C51H79NO13
p/n and sizes: R1329-10g, R1329-50g, &
Rifampicin is active against gram-positive bacteria but less active against gram-negative
bacteria. It interferes with the synthesis of nucleic acids by inhibiting DNA dependent RNA polymerase.
Resistance to rifampicin can develop rapidly. The degree of resistance varies depending on the site of
mutation in the RNA polymerase. For research use.
Molecular Weight: 822.94
Molecular Formula: C43H58N4O12
p/n and sizes: R9001-250mg, R9001-1g, &
Ribonuclease A (RNase A) is an endoribonuclease, that specifically cleaves single-stranded
RNA 3' to pyrimidine residues (cytosine, uracil). Thereby, it generates pyrimidine-3'-phosphate or oligonucleotides
with terminal pyrimidine-3'-phosphates. A major application for RNAse A is the removal of RNA from preparations of
plasmid DNA. For this application, DNAse free RNAse A is recommended to be used at a final concentration of 10
ug/ml. For research use.
Source: Bovine pancreas.
Specific Activity: >60
p/n and sizes: R3810-250g &
Streptomycin was isolated from Streptomyces griseus. It acts bacteriostatic at low concentrations and
bactericidal at higher concentrations against mycobacteria and gram negative bacteria. It is less active against
gram positve bacteria. Like other antibiotics, streptomyicin does not act on non-proliferating microorganism.
Streptomycin leads to reading error during translation due to the interaction with 23S RNA of the 30S
ribosomes. For research use.
Potency: >720 IU/mg
pH(20%, water, 25°C):
Molecular Formula: (C21H39N7O12)2 .3H2O4S)
TAPS (3-[ Tris(hydroxymethyl)methylamino]-1-propane sulfonic
p/n and sizes: R2991-250g & Bulk
Molecular Biology Buffer. For resaerch use.
Molecular Weight: 243.28
Molecular Formula: C7H17NO6S
TES (2-[Tris-(hydroxymethyl)methylamino]-1-ethane sulfonic
p/n and sizes: R7365-250g &
Molecular Biology Buffer. For research use.
Molecular Weight: 229.25
Molecular Formula: C6H15NO6S
Tricine (N-[ Tris-(Hydroxymethyl)-Methyl
p/n and sizes: R5704-500g & Bulk
Molecular Biology Buffer. Buffer component for separation of low molecular weight
peptides. For research use.
Molecular Weight: 179.17
Tris ((hydroxymethyl) aminomethane)
p/n and sizes: R7786-Bulk
Molecular Biology Buffer. Aminopeptidase substrat. For research use.
Molecular Weight: 121.14
Molecular Formula: NH2C(CH2OH)3
p/n and sizes: R1404-2g,
R1404-10g, & Bulk
Vancomycin is a glycopeptide antibiotic. It excerts its action by inhibiting the formation of
the peptidoglycan polymers of the bacterial cell wall. Unlike penicillins that act primarily to prevent the
crosslinking of peptidoglycans that give the cell its strength, vancomycin prevents the transfer and addition of
the muramylpentapeptide building blocks that form the peptidoglycan molecular itself. Vancomycin is often used in
combination with cefotaxim or carbenicillin to obtain a synergism in antimicrobial activity against bacteria.
Especially used by Agrobacterium species with b-lactamase production. For research use.
Molecular Formula: C66H75Cl2N9O24 ·
p/n and sizes: R7240-1g &
X-Gal is a chromogenic substrate of b-Galactosidase. It is used in conjunction with IPTG for
detection of b-Galactosidase activity in bacterial colonies in a colorimetric assay to detect recombinants (white)
from non-recombinants (blue). X-Gal is cleaved at the b 1-4 bond between galactose and the
5-Bromo-4-chloro-3-indolyl part of X-Gal by b-Glactosidase via hydrolysis. The cleavage of X-Gal results in
the production of a water insoluble blue dichloro-dibromo-indigo precipitate at the site of enzymatic
cleavage. In cloning strategies with vectors such as Lamda-11, M13mp18 and 19 and 19, pUC18 and 19, pUR222
the E.Coli lacZ gene is transformed to lac cells. After transformation the cells show b-Galactosidase activity in
the presence of IPTG and X-Gal containing media. The insertion of a DNA fragment into the cloning sites of the lacZ
gene results in the disruption of b-Galactosidase activity leading to the appearance of white colonies on X-Gal and
IPTG containing media. Non recombinant cells produce a blue indigo dye on these media. For research use.
Solubility: 2% Soln. in DMF
Molecular Formula: C14H15BrClNO6
X-Glucuro Sodium Salt (5-Bromo-4-Chloro-3-Indolyl-β-D-Glucuronide)
p/n and sizes: R1295-100mg,
R1295-1g, & Bulk
Substrate for β-Glucuronidase. It is converted by the enzyme into an intense blue precipitate. It is used for the
detection of the GUS gene in bacterial colonies, e.g. Escherichia coli, or for histochemical applications. For
Molecular Formula: C14H12BrClNO7Na
Molecular Weight: 444.6